Publications

publications by categories in reversed chronological order. generated by jekyll-scholar.

2025

  1. Patent
    Ultra ph-sensitive micelles encapsulating cytokines for treatment of cancer
    Jinming Gao, Gang Huang, SUN Zhichen, Qiang Feng, and Wei Li
    2025
    US Patent App. 18/710,555
  2. STAR Protocols
    mask2SC.jpg
    Protocol for integrating immunohistochemistry and H&E annotations with Xenium data at single-cell resolution
    Jun Chen, William Hartnett, Vijay S Basava, Maximilian Lee, Baran D Sumer, Jinming Gao, and Qiang Feng
    STAR protocols, 2025
    DOI
  3. under review
    Homing and Detection of Unknown Primary Head-Neck Cancer by Acid-Sensing Nanoparticles
    Jinming Gao, Qiang Feng, Jun Chen, William Hartnett, Sindhu Voorugonda, Brittny Tillman, John Truelson, Larry Myers, Andrew Day, Vijay Basava, and others
    2025
    DOI
  4. A Multi-Threshold Micelle Improves Tumor Accumulation and STING Immunotherapy
    Zachary T Bennett, Animeshasavithri Krishnamurthy, Shuyue Ye, Vijay S Basava, Qiang Feng, Gang Huang, Baran D Sumer, and Jinming Gao
    Journal of the American Chemical Society, 2025
    DOI
  5. TMPRSS11B promotes an acidified microenvironment and immune suppression in squamous lung cancer
    Hari Shankar Sunil, Jean R Clemenceau, Anthony Grichuk, Isabel Barnfather, Sumanth R Nakkireddy, Luke Izzo, Qiang Feng, William Hartnett, Bret M Evers, Lisa Thomas, and others
    EMBO reports, 2025
    DOI
  6. Stimuli-responsive STING nanovaccine for systemic therapy of HPV-induced cancers
    Shuang Chen, Shuyue Ye, Gang Huang, Zhichen Sun, Qiang Feng, Maggie Wang, Raymundo Pantoja, Baran D Sumer, and Jinming Gao
    Proceedings of the National Academy of Sciences, 2025
    DOI

2024

  1. Nature BME
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    Severely polarized extracellular acidity around tumour cells
    Qiang Feng, Zachary Bennett, Anthony Grichuk, Raymundo Pantoja, Tongyi Huang, Brandon Faubert, Gang Huang, Mingyi Chen, Ralph J DeBerardinis, Baran D Sumer, and Jinming Gao
    Nature Biomedical Engineering, 2024
    DOI
  2. Thermophoretic glycan profiling of extracellular vesicles for triple-negative breast cancer management
    Yike Li, Shaohua Zhang, Chao Liu, Jinqi Deng, Fei Tian, Qiang Feng, Lili Qin, Lixiao Bai, Ting Fu, Liqin Zhang, and others
    Nature Communications, 2024
    DOI

2023

  1. Elucidation of Protonation Cooperativity of a STING-Activating Polymer
    Maggie Wang, Zachary T Bennett, Parnavi Singh, Qiang Feng, Jonathan Wilhelm, Gang Huang, and Jinming Gao
    Advanced Materials, 2023
    DOI
  2. Nano Res
    ZIF.png
    Microfluidic one-step, aqueous synthesis of size-tunable zeolitic imidazolate framework-8 for protein delivery
    Wenxing Lv, Ziwei Han, Shaokun Dong, Yanjuan Huang, Jinqi Deng, Chao Liu, Qiang Feng, and Jiashu Sun
    Nano Research, 2023
    Qiang Feng and Jiashu Sun are co-corresponding authors
    DOI
  3. Nanoscale Horiz
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    Microfluidic synthesis of nanomaterials for biomedical applications
    Yanjuan Huang, Chao Liu, Qiang Feng, and Jiashu Sun
    Nanoscale Horizons, 2023
    Qiang Feng and Jiashu Sun are co-corresponding authors
    DOI

2022

  1. Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification
    Zhenzhen Zi, Zhuzhen Zhang, Qiang Feng, Chiho Kim, Xu-Dong Wang, Philipp E Scherer, Jinming Gao, Beth Levine, and Yonghao Yu
    Nature communications, 2022
    DOI
  2. Nature Comm
    Lactate.png
    Lactate increases stemness of CD8+ T cells to augment anti-tumor immunity
    Qiang Feng, Zhida Liu, Xuexin Yu, Tongyi Huang, Jiahui Chen, Jian Wang, Jonathan Wilhelm, Suxin Li, Jiwon Song, Wei Li, Zhichen Sun, Baran D Sumer, Bo Li, Yang-Xin Fu, and Jinming Gao
    Nature communications, 2022
    Qiang Feng, Zhida Liu and Xuexin Yu contributed equally
    DOI

2021

  1. AHM
    MCT1.jpg
    Tumor-Targeted Inhibition of Monocarboxylate Transporter 1 Improves T-Cell Immunotherapy of Solid Tumors
    Tongyi Huang, Qiang Feng, Zhaohui Wang, Wei Li, Zhichen Sun, Jonathan Wilhelm, Gang Huang, Tram Vo, Baran D Sumer, and Jinming Gao
    Advanced Healthcare Materials, 2021
    Tongyi Huang and Qiang Feng contributed equally
    DOI
  2. Prolonged activation of innate immune pathways by a polyvalent STING agonist
    Suxin Li, Min Luo, Zhaohui Wang, Qiang Feng, Jonathan Wilhelm, Xu Wang, Wei Li, Jian Wang, Agnieszka Cholka, Yang-xin Fu, and others
    Nature biomedical engineering, 2021
    DOI
  3. Enhancing gene editing efficiency for cells by CRISPR/Cas9 system-loaded multilayered nanoparticles assembled via microfluidics
    Xuanyu Li, Qiang Feng, Ziwei Han, and Xingyu Jiang
    Chinese Journal of Chemical Engineering, 2021
    Xuanyu Li, Qiang Feng and Ziwei Han contributed equally
    DOI
  4. Multilayer Ratiometric Fluorescent Nanomachines for Imaging mRNA in Live Cells
    Jianqiao Chang, Yu Zhang, Yike Li, Ziwei Han, Fei Tian, Chao Liu, Qiang Feng, Yuguang Wang, Jiashu Sun, and Lu Zhang
    Small Methods, 2021
    Qiang Feng, Yuguang Wang and Lu Zhang are co-corresponding authors
    DOI
  5. Patent
    PH responsive block copolymer compositions and micelles that inhibit MCT 1 and related proteins
    2021
    US Patent App. 17/239,742

2020

  1. Detection of Lymph Node Metastases by Ultra-pH-Sensitive Polymeric Nanoparticles
    Zachary T Bennett, Qiang Feng, Justin A Bishop, Gang Huang, Baran D Sumer, and Jinming Gao
    Theranostics, 2020
    DOI

2019

  1. Lipid nanovesicles by microfluidics: manipulation, synthesis, and drug delivery
    Chao Liu, Qiang Feng, and Jiashu Sun
    Advanced Materials, 2019
    Chao Liu, Qiang Feng contributed equally
    DOI
  2. Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers
    Chao Liu, Junxiang Zhao, Fei Tian, Lili Cai, Wei Zhang, Qiang Feng, Jianqiao Chang, Fangning Wan, Yunjie Yang, Bo Dai, and others
    Nature biomedical engineering, 2019
    DOI
  3. Accounts
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    Transistor-like Ultra-pH-Sensitive Polymeric Nanoparticles
    Qiang Feng, Jonathan Wilhelm, and Jinming Gao
    Accounts of chemical research, 2019
    DOI
  4. Manipulation of bio-micro/nanoparticles in non-Newtonian microflows
    Fei Tian, Qiang Feng, Qinghua Chen, Chao Liu, Tiejun Li, and Jiashu Sun
    Microfluidics and Nanofluidics, 2019
    DOI
  5. Microfluidic Synthesis of Gd-Based Nanoparticles for Fast and Ultralong MRI Signals in the Solid Tumor
    Xuanyu Li, Qiang Feng, and Xingyu Jiang
    Advanced healthcare materials, 2019
    DOI

2018

  1. Thermo-triggered Release of CRISPR-Cas9 System by Lipid-Encapsulated Gold Nanoparticles for Tumor Therapy
    Peng Wang, Lingmin Zhang, Wenfu Zheng, Liman Cong, Zhaorong Guo, Yangzhouyun Xie, Le Wang, Rongbing Tang, Qiang Feng, Yoh Hamada, and others
    Angewandte Chemie International Edition, 2018
    DOI
  2. Hand-powered centrifugal microfluidic platform inspired by the spinning top for sample-to-answer diagnostics of nucleic acids
    Lu Zhang, Fei Tian, Chao Liu, Qiang Feng, Tingxuan Ma, Zishan Zhao, Tiejun Li, Xingyu Jiang, and Jiashu Sun
    Lab on a Chip, 2018
    DOI
  3. Control over the emerging chirality in supramolecular gels and solutions by chiral microvortices in milliseconds
    Jiashu Sun, Yike Li, Fusheng Yan, Chao Liu, Yutao Sang, Fei Tian, Qiang Feng, Pengfei Duan, Li Zhang, Xinghua Shi, and others
    Nature communications, 2018
    DOI
  4. Nanocatalyst Complex Can Dephosphorylate Key Proteins in MAPK Pathway for Cancer Therapy
    Rongbing Tang, Yuexiao Jia, Wenshu Zheng, Qiang Feng, Wenfu Zheng, and Xingyu Jiang
    Advanced healthcare materials, 2018
    DOI

2017

  1. Small
    Small.jpg
    One-Step Microfluidic Synthesis of Nanocomplex with Tunable Rigidity and Acid-Switchable Surface Charge for Overcoming Drug Resistance
    Qiang Feng, Jianping Liu, Xuanyu Li, Qinghua Chen, Jiashu Sun, Xinghua Shi, Baoquan Ding, Haijun Yu, Yaping Li, and Xingyu Jiang
    Small, 2017
    Qiang Feng and Jianping Liu contributed equally
    DOI
  2. Point-of-care-testing of nucleic acids by microfluidics
    Lu Zhang, Baozhi Ding, Qinghua Chen, Qiang Feng, Ling Lin, and Jiashu Sun
    TrAC Trends in Analytical Chemistry, 2017
    DOI
  3. Integrated Microfluidic Platform with Multiple Functions To Probe Tumor–Endothelial Cell Interaction
    Ling Lin, Xuexia Lin, Luyao Lin, Qiang Feng, Takehiko Kitamori, Jin-Ming Lin, and Jiashu Sun
    Analytical Chemistry, 2017
    DOI
  4. Lipid nanoparticle-mediated efficient delivery of CRISPR/Cas9 for tumor therapy
    Lingmin Zhang, Peng Wang, Qiang Feng, Nuoxin Wang, Zitian Chen, Yanyi Huang, Wenfu Zheng, and Xingyu Jiang
    NPG Asia Materials, 2017
    DOI

2016

  1. Microfluidics-mediated assembly of functional nanoparticles for cancer-related pharmaceutical applications
    Qiang Feng, Jiashu Sun, and Xingyu Jiang
    Nanoscale, 2016
    DOI
  2. Nanocrystalline cellulose improves the biocompatibility and reduces the wear debris of ultrahigh molecular weight polyethylene via weak binding
    Shiwen Wang, Qiang Feng, Jiashu Sun, Feng Gao, Wei Fan, Zhong Zhang, Xiaohong Li, and Xingyu Jiang
    Acs Nano, 2016
    DOI
  3. Quantitative detection of microRNA in one step via next generation magnetic relaxation switch sensing
    Wenjing Lu, Yiping Chen, Zhong Liu, Wenbo Tang, Qiang Feng, Jiashu Sun, and Xingyu Jiang
    Acs Nano, 2016
    DOI

2015

  1. Microfluidic based high throughput synthesis of lipid-polymer hybrid nanoparticles with tunable diameters
    Qiang Feng, Lu Zhang, Chao Liu, Xuanyu Li, Guoqing Hu, Jiashu Sun, and Xingyu Jiang
    Biomicrofluidics, 2015
    Qiang Feng, Lu Zhang and Liu Chao contributed equally
    DOI
  2. Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell–Nanoparticle Interaction
    Lu Zhang, Qiang Feng, Jiuling Wang, Shuai Zhang, Baoquan Ding, Yujie Wei, Mingdong Dong, Ji-Young Ryu, Tae-Young Yoon, Xinghua Shi, Jiashu Sun, and Xingyu Jiang
    ACS nano, 2015
    Lu Zhang, Qiang Feng, Jiuling Wang contributed equally
    DOI
  3. Angew
    RNV.jpg
    Microfluidic synthesis of rigid nanovesicles for hydrophilic reagents delivery
    Lu Zhang, Qiang Feng, Jiuling Wang, Jiashu Sun, Xinghua Shi, and Xingyu Jiang
    Angewandte Chemie International Edition, 2015
    Lu Zhang, Qiang Feng, and Jiuling Wang contributed equally
    DOI

2014

  1. Core-shell type lipid/rPAA-Chol polymer hybrid nanoparticles for in vivo siRNA delivery
    Ling-Yan Gao, Xiao-Yan Liu, Cheng-Jun Chen, Jian-Cheng Wang, Qiang Feng, Min-Zhi Yu, Xiao-Fei Ma, Xi-Wei Pei, Yu-Jie Niu, Chong Qiu, and others
    Biomaterials, 2014
    DOI
  2. Synergistic inhibition of breast cancer by co-delivery of VEGF siRNA and paclitaxel via vapreotide-modified core–shell nanoparticles
    Qiang Feng, Min-Zhi Yu, Jian-Cheng Wang, Wen-Jie Hou, Ling-Yan Gao, Xiao-Fei Ma, Xi-Wei Pei, Yu-Jie Niu, Xiao-Yan Liu, Chong Qiu, and others
    Biomaterials, 2014
    Qiang Feng, and Min-Zhi Yu contributed equally
    DOI
  3. Integrated Microcapillary for Sample-to-Answer Nucleic Acid Pretreatment, Amplification, and Detection
    Lu Zhang, Yi Zhang, Chunyan Wang, Qiang Feng, Fei Fan, Guojun Zhang, Xixiong Kang, Xuzhen Qin, Jiashu Sun, Yinghui Li, and others
    Analytical chemistry, 2014
    DOI
  4. Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake
    Jiashu Sun, Lu Zhang, Jiuling Wang, Qiang Feng, Dingbin Liu, Qifang Yin, Dongyan Xu, Yujie Wei, Baoquan Ding, Xinghua Shi, and others
    Advanced materials (deerfield beach, fla.), 2014
    DOI

2013

  1. Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly (amidoamine) for siRNA delivery
    Cheng-Jun Chen, Jian-Cheng Wang, En-Yu Zhao, Ling-Yan Gao, Qiang Feng, Xiao-Yan Liu, Zhi-Xia Zhao, Xiao-Fei Ma, Wen-Jie Hou, Liang-Ren Zhang, and others
    Biomaterials, 2013
    DOI

2012

  1. Surface engineering of gold nanoparticles for in vitro siRNA delivery
    Enyu Zhao, Zhixia Zhao, Jiancheng Wang, Chunhui Yang, Chengjun Chen, Lingyan Gao, Qiang Feng, Wenjie Hou, Mingyuan Gao, and Qiang Zhang
    Nanoscale, 2012
    DOI
  2. Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine (R 15) triblock copolymer for siRNA delivery
    Zhi-Xia Zhao, Shan-Yun Gao, Jian-Cheng Wang, Cheng-Jun Chen, En-Yu Zhao, Wen-Jie Hou, Qiang Feng, Ling-Yan Gao, Xiao-Yan Liu, Liang-Ren Zhang, and others
    Biomaterials, 2012
    DOI
  3. Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo
    Xiao-Mei Tao, Jian-cheng Wang, Jia-bao Wang, Qiang Feng, Shan-yun Gao, Liang-Ren Zhang, and Qiang Zhang
    European Journal of Pharmaceutics and Biopharmaceutics, 2012
    DOI
  4. Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine (R₁₅) triblock copolymer for siRNA delivery
    Zhi-Xia Zhao, Shan-Yun Gao, Jian-Cheng Wang, Cheng-Jun Chen, En-Yu Zhao, Wen-Jie Hou, Qiang Feng, Ling-Yan Gao, Xiao-Yan Liu, Liang-Ren Zhang, and others
    2012
    DOI